Coumarins and derivatives
Selleck Chemical LLC 7-Methoxycoumarin S5163-25mg
7-Methoxycoumarin (Herniarine) also known as Herniarin is a methoxy derivative of coumarin and substrate for dealkylase It has been used in the synthesis of anti-first-pass effect compounds and detergents
Apexbio Technology LLC HX 531 188844-34-0 10mg
HX 531 (CAS 188844-34-0) is a small-molecule antagonist targeting the retinoid X receptor (RXR) It modulates RXR-associated signaling pathways thereby influencing both tumorigenic and metabolic biological processes HX 531 exerts its biological activity by antagonizing RXR which results in cell cycle arrest at the G0/G1 phase and modulation of leptin-dependent pathways and the p53-p21Cip1 signaling axis In rodent models HX 531 demonstrates an inhibitory activity with an IC50 value of approximately 18 nM Based on these pharmacological properties HX 531 holds research potential in the study of metabolic disorders obesity diabetes and cancer biology
Apexbio Technology LLC Coumarin 91-64-5 50mg
Coumarin (91-64-5) is a small-molecule inhibitor targeting cytochrome P450 isoforms It is designed to modulate enzyme activity thereby regulating metabolic pathways Coumarin exerts its biological activity primarily through inhibition of cytochrome P450 enzymes In in vitro studies coumarin demonstrates enzyme inhibitory activity with an IC50 range of approximately 0 5 to 10 M depending on the isoform and experimental system Based on these pharmacological properties coumarin holds research potential in anticoagulant anti-inflammatory and anticancer agent discovery
Medchemexpress LLC 7-methoxycoumarin-3-carboxylic acid | 20300-59-8 | MFCD00452770 | 97.0% | 220.18 | C11H8O5 | 250 MG
7-Methoxycoumarin-3-carboxylic acid is a coumarin-based fluorescent dye used to derivatize molecules for fluorescence detection in biochemical assays. It is commonly applied to label peptides, for HPLC derivatization, and for development of fluorescent probes.
- Fluorescent coumarin dye with characteristic excitation and emission peaks.
- Excitation ~345-355 nm; emission ~405-450 nm.
- High purity (manufacturer lists 97.0%).
- Chemical formula C11H8O5; molecular weight 220.18.
- Available in multiple sizes from 250 mg to 50 g.
- Suitable for peptide labeling and HPLC derivatization.
- Supplied with data sheet and safety data sheet (SDS).
Apexbio Technology LLC 3-Carboxy-7-Hydroxycoumarin 779-27-1 100mg
3-Carboxy-7-Hydroxycoumarin (CAS 779-27-1) is a coumarin-based fluorescent molecule It is characterized by blue fluorescence emission upon excitation with ultraviolet light Structurally it features a carboxyl group that enables conjugation via carbodiimide activation (e g EDAC-mediated formation of succinimidyl ester intermediates) allowing covalent attachment to amine-containing residues in proteins and nucleic acids Based on these properties 3-Carboxy-7-Hydroxycoumarin is commonly employed in biochemical research for fluorescent labeling including analysis of protein protein interactions nucleic acid visualization and biomolecule detection assays
Apexbio Technology LLC 3-Carboxy-7-Hydroxycoumarin 779-27-1 250mg
3-Carboxy-7-Hydroxycoumarin (CAS 779-27-1) is a coumarin-based fluorescent molecule It is characterized by blue fluorescence emission upon excitation with ultraviolet light Structurally it features a carboxyl group that enables conjugation via carbodiimide activation (e g EDAC-mediated formation of succinimidyl ester intermediates) allowing covalent attachment to amine-containing residues in proteins and nucleic acids Based on these properties 3-Carboxy-7-Hydroxycoumarin is commonly employed in biochemical research for fluorescent labeling including analysis of protein protein interactions nucleic acid visualization and biomolecule detection assays
Chem-Impex International, Inc. 4-Methylumbelliferyl acetate | MFCD00006865 | 1G
4-Methylumbelliferyl acetate, MFCD00006865, 1G
Sigma Aldrich Fine Chemicals Biosciences 7-Ethoxycoumarin | 31005-02-4 | MFCD00006877 | 100MG
7-Ethoxycoumarin | Purity: >=99.45% (HPLC) | Mol Wt: 190.2 | 31005-02-4 | MFCD00006877 | 100MG
Cayman Chemical 3azido7hydroxy Coumarin
A click-reactive fluorescent dye; Upon CuAAC in a biological system, a fluorescent product is produced that displays excitation/emission maxima of 404 and 477 nM, respectively; has been used for spatially restricted metabolite labeling and the detection of foodborne pathogens
![Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261568.png-250.jpg)
Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG
Palomid 529 is a small-molecule research inhibitor that targets both mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2), modulating the PI3K/Akt/mTOR signaling pathway. It has been used in preclinical studies and early clinical research to reduce tumor growth, angiogenesis, and vascular permeability, and has been investigated for neovascular age-related macular degeneration.
- Dual inhibition of mTORC1 and mTORC2.
- Documented in peer-reviewed literature and public chemical databases.
- High reported purity suitable for analytical use.
- Suitable as an analytical standard and research reagent.
- Provided with batch-specific certificate of analysis data.