Coumarins and derivatives
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 1G
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 1G
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 500MG
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 500MG
Sigma Aldrich Fine Chemicals Biosciences Scopoletin >=99% | 92-61-5 | MFCD00006872 | 50MG
Scopoletin >=99% | Purity: >=99% | Mol Wt: 192.17 | 92-61-5 | MFCD00006872 | 50MG
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin suitable for fluorescence, >=98.0% (TLC) | 531-59-9 | MFCD00006876 | 500MG
7-Methoxycoumarin suitable for fluorescence, >=98.0% (TLC) | Purity: >=98.0% (TLC) | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 | 500MG
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin >=98% | 531-59-9 | MFCD00006876 | 25G
7-Methoxycoumarin >=98% | Purity: >=98% | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 | 25G
Sigma Aldrich Fine Chemicals Biosciences 7-Methoxycoumarin >=98% | 531-59-9 | MFCD00006876 |
7-Methoxycoumarin >=98% | Purity: >=98% | Mol Wt: 176.17 | 531-59-9 | MFCD00006876 |
Sigma Aldrich Fine Chemicals Biosciences 7-Diethylamino-4-methylcoumarin 99% | 91-44-1 | MFCD00006864 | 100G
7-Diethylamino-4-methylcoumarin 99% | Purity: 99% | Mol Wt: 231.29 | 91-44-1 | MFCD00006864 | 100G
Cayman Chemical 7-EthoxycoumarIn 500mg
A CYP450 substrate; undergoes O-deethylation by various CYP isoforms; has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea
Medchemexpress LLC 3-Nitrocoumarin | 28448-04-6 | 100.0% | 191.14 | 1 ML
3-Nitrocoumarin is an inhibitor for phospholipase C that blocks the generation of inositol triphosphate (IP3), thereby affecting the calcium signaling pathway. This compound causes morphological changes of apical hyperbranching in *N. crassa* hyphae.
- Inhibits phospholipase C, affecting the calcium signaling pathway.
- Inhibits glucose-induced increase of intracellular calcium ions in yeast strain WPY260 (at 50 mg/mL for 6 min).
- Inhibits PLC in *Neurospora crassa* with an IC50 of 10 μg/mL.
- Inhibits the growth of *N. crassa* and causes morphological changes of apical hyperbranching in hyphae.
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 50 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase (LOX), with an IC50 for recombinant human tyrosinase (rHT) of 26 μM and an IC50 for LOX of 9.5 μM. It exhibits DPPH free radical scavenging activity and has photoprotective effects on sea urchin zygotes and embryos. The compound has also demonstrated anticancer activity against human SK-MEL-28 cells and SK-MEL3 cells in vitro.
- Inhibits tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Provides photoprotective effects on sea urchin zygotes and embryos
- Shows anticancer activity against human SK-MEL-28 and SK-MEL3 cells
- Can be formulated into a vesicle delivery system for topical administration
Medchemexpress LLC 3-Hydroxycoumarin | 939-19-5 | 99.3% | 250 MG
3-Hydroxycoumarin is an inhibitor of tyrosinase and lipoxygenase, with an IC50 of 26 μM for recombinant human tyrosinase (rHT) and a Ki of 3.39 μM. It also demonstrates DPPH free radical scavenging activity (IC50 = 31.2 μM) and has photoprotective effects on sea urchin zygotes and embryos. This compound can be developed into a vesicle delivery system for local administration to achieve efficient local accumulation in the skin, facilitating the study of diseases related to excessive skin pigmentation.
- Acts as an inhibitor of tyrosinase and lipoxygenase
- Exhibits DPPH free radical scavenging activity
- Offers photoprotective effects on sea urchin zygotes and embryos
- Can be formulated into a vesicle delivery system for topical applications
- Effective in inhibiting the first cleavage of sea urchin embryos in a concentration-dependent manner